Zepbound (tirzepatide) is a GLP-1/GIP medication approved for weight management. As usage expands, some patients have reported severe and sometimes life-altering complications — including gastroparesis (stomach paralysis), intestinal obstruction, pancreatitis, gallbladder disease, dehydration-related kidney injury, and long-term digestive impairment. Many affected individuals are now exploring potential legal claims.
This page outlines the injuries most often associated with Zepbound-related claims, how eligibility is evaluated, and what evidence typically matters during case review.
Why Zepbound Lawsuits Are Emerging
Claim reviews and investigations commonly focus on allegations that:
- patients were not clearly warned about the risk of severe GI motility disorders
- nausea and vomiting were presented as “temporary” even when they can become chronic
- rapid weight loss and prolonged appetite suppression contributed to gallbladder complications
- dehydration from vomiting contributed to kidney injury
- long-term safety outcomes for broad population use remain incomplete
Many patients state they used Zepbound as prescribed but experienced unexpectedly severe outcomes requiring emergency treatment.
Injuries Commonly Reported in Zepbound Claims
Gastroparesis (Stomach Paralysis)
A leading injury in GLP-1 legal screenings.
Reported symptoms include:
- chronic nausea
- vomiting undigested food
- extreme fullness after small meals
- inability to tolerate solid foods
- motility testing confirming delayed emptying
- long-term dietary restriction and disability
➡️ Legal hub: Gastroparesis
Intestinal Obstruction & Severe Motility Disorders
Some cases involve severe slowing throughout the digestive tract, resulting in:
- inability to pass stool or gas
- abdominal swelling and pain
- severe constipation or bowel shutdown
- hospitalization and imaging
- surgical evaluation or intervention
➡️ Legal hub: Intestinal Obstruction
Pancreatitis
Reported complications include:
- intense upper abdominal pain radiating to the back
- vomiting, fever
- elevated pancreatic enzymes
- hospitalization and IV therapy
- recurrence or chronic pancreatic impairment in some cases
➡️ Legal hub: Pancreatitis
Kidney Injury & Kidney Failure (Often Dehydration-Driven)
Kidney injury may develop after:
- prolonged vomiting
- persistent dehydration
- electrolyte imbalance
- pancreatitis complications
Possible findings:
- AKI
- reduced eGFR
- elevated creatinine
- hospitalization for IV fluids
- dialysis (severe cases)
➡️ Legal hub: Kidney Failure
Gallbladder Disease & Removal
Because Zepbound can cause rapid, significant weight loss, reported gallbladder events include:
- gallstones
- gallbladder inflammation
- bile duct obstruction
- gallbladder removal surgery
- persistent digestive symptoms after surgery
➡️ Legal hub: Gallbladder Removal
Patterns Seen in Zepbound Case Evaluations
Legal screenings often identify patterns such as:
- worsening vomiting after dose escalation
- extended inability to tolerate normal meals
- repeated ER visits for dehydration
- documented motility dysfunction
- measurable kidney decline following vomiting episodes
- gallbladder crises after rapid weight loss
- symptoms persisting after discontinuation
Objective documentation (imaging, labs, motility testing) frequently strengthens claim eligibility.
Who May Qualify for a Zepbound Injury Claim
You may qualify if:
- you used Zepbound, AND
- you developed a serious complication requiring treatment, AND
- you experienced long-term harm or significant disruption to daily life
Common potentially qualifying diagnoses include:
- confirmed gastroparesis or delayed gastric emptying
- intestinal obstruction or severe motility disorder
- pancreatitis
- kidney injury or kidney failure
- gallbladder disease or gallbladder removal
- chronic vomiting with hospitalization
- long-term nutritional impairment or disability
If your condition impacted work, independence, or normal eating, a case review may be warranted.
Evidence That Strengthens Zepbound Claims
Strong claim reviews typically include:
- GI testing (gastric emptying scan, motility studies)
- abdominal imaging (CT/MRI/ultrasound)
- pancreatic enzyme labs (lipase/amylase)
- kidney function labs (creatinine, eGFR, BUN)
- gallbladder imaging and surgical notes
- ER/hospital admission and discharge records
- specialist notes (GI, nephrology, surgery)
- prescription and dose history for Zepbound
- documentation showing symptoms persisted after stopping
➡️ Evidence checklist: Medical Records
Potential Compensation in Zepbound Lawsuits
Depending on severity and documentation, compensation may address:
- medical bills, hospitalizations, and ER care
- diagnostic tests and specialist treatment
- surgery costs (gallbladder removal, feeding interventions)
- kidney-related treatment, including dialysis
- long-term medication and follow-up care
- lost wages and reduced earning capacity
- disability, pain, suffering, and emotional distress
- diminished quality of life
➡️ More: Compensation
Timeline & Causation Factors Considered
Reviews commonly look at:
- symptom onset after starting Zepbound
- symptom escalation after dose changes
- persistence of symptoms after stopping
- objective diagnostics confirming injury
- length of hospitalization and follow-up impairment
These details help establish whether the medication likely contributed to the injury pattern.
When to Seek Medical & Legal Help
Consider urgent medical care and legal evaluation if you experienced:
- persistent vomiting or inability to keep fluids down
- severe abdominal pain
- dehydration requiring IV fluids
- reduced urination or swelling
- diagnosis of gastroparesis, pancreatitis, bowel obstruction, kidney injury, or gallbladder disease
- surgery (especially gallbladder removal)
- ongoing inability to eat normally months after stopping
How to Start a Zepbound Claim Review
To begin, you generally need to share:
- your Zepbound use timeline (start/stop, dose pattern)
- your main symptoms or diagnosis
- medical care received (ER, hospitalization, surgery)
- whether your condition is ongoing
➡️ Start your review: File a Claim
➡️ Check criteria: Criteria